Overlap of obsessive and posttraumatic symptoms: A systematic review
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Abstract
Objective. The key aim of this work was to deliver a comprehensive overview of empirical and observational studies concerning the overlap between both psychopathologies.
Method. Two independent authors searched PubMed, PsycINFO, and Web of Science databases between April and July 2020 utilizing relevant MeSH terms. Subsequently, a systematic scoping review was undertaken according to the PRISMA-ScR Statement to identify all relevant publications concerning the overlap of OCD and PTSD symptomatology. We included peer reviewed studies published in any language that contributed quantitative or qualitative data that addressed the relationship between OCD and PTSD symptoms as the main aim or outcome of the study. Non-peer-reviewed articles, studies that did not address this phenomenon of interest, and gray literature documents were excluded. This review was not registered into the International Prospective Register of Systematic Reviews, since, according to the National Institute of Health Research, scoping reviews are ineligible for registration into PROSPERO.
Results. Twenty-five relevant studies were included (11 cross-sectional studies, 5 longitudinal-prospective studies, 4 case series, 4 case studies and 1 retrospective study). We did not conduct any statistical analysis due to the diversity of the included studies, thus proceeding to realize a thematic synthesis of the obtained data.
Discussion and conclusion. A symptomatic overlap exists between both comorbidities in some clinical populations, and this relationship may hamper treatment outcomes.
References
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th edition). Washington, DC.: American Psychiatric Publishing.
Araújo, A. X. G. de, Fontenelle, L. F., Berger, W., Luz, M. P. da, Pagotto, L. F. A. da C., Marques-Portella, C., … Mendlowicz, M. V. (2018). Pre-traumatic vs post-traumatic OCD in PTSD patients: Are differences in comorbidity rates and functional health status related to childhood abuse? Comprehensive Psychiatry, 87, 25-31. doi: 10.1016/j.comppsych.2018.08.012
Badour, C. L., Bown, S., Adams, T. G., Bunaciu, L., & Feldner, M. T. (2012). Specificity of fear and disgust experienced during traumatic interpersonal victimization in predicting posttraumatic stress and contamination-based obsessive-compulsive symptoms. Journal of Anxiety Disorders, 26(5), 590-598. doi: 10.1016/j.janxdis.2012.03.001
Cohen, J., Mychailyszyn, M., Settipani, C., Crawley, S., & Kendall, P. C. (2011). Issues in Differential Diagnosis: Considering Generalized Anxiety Disorder, Obsessive-Compulsive Disorder, and Posttraumatic Stress Disorder. In Handbook of Child and Adolescent Anxiety Disorders (pp. 23-35). New York: Springer. doi: 10.1007/978-1-4419-7784-7_3
Cromer, K. R., Schmidt, N. B., & Murphy, D. L. (2007). An investigation of traumatic life events and obsessive-compulsive disorder. Behaviour Research and Therapy, 45(7), 1683-1691. doi: 10.1016/j.brat.2006.08.018
de Moraes, E. C., Torresan, R. C., Trench, E. V., & Torres, A. R. (2008). A possible case of posttraumatic obsessive-compulsive disorder. Revista Brasileira de Psiquiatria, 30, 291. doi: 10.1590/S1516-44462008000300018
de Silva, P., & Marks, M. (2001). Traumatic experiences, post-traumatic stress disorder and obsessive-compulsive disorder. International Review of Psychiatry, 13(3), 172-180. doi: 10.1080/09540260120074037
Ehring, T., Ehlers, A., & Glucksman, E. (2008). Do Cognitive Models Help in Predicting the Severity of Posttraumatic Stress Disorder, Phobia, and Depression After Motor Vehicle Accidents? A Prospective Longitudinal Study. Journal of Consulting and Clinical Psychology, 76(2), 219-230. doi: 10.1037/0022-006X.76.2.219
Fontenelle, L. F., Cocchi, L., Harrison, B. J., Shavitt, R. G., do Rosário, M. C., Ferrão, Y. A., … Torres, A. R. (2012). Towards a post-traumatic subtype of obsessive-compulsive disorder. Journal of Anxiety Disorders, 26(2), 377-383. doi: 10.1016/j.janxdis.2011.12.001
Fostick, L., Nacasch, N., & Zohar, J. (2012). Acute obsessive compulsive disorder (OCD) in veterans with posttraumatic stress disorder (PTSD). World Journal of Biological Psychiatry, 13(4), 312-315. doi: 10.3109/15622975.2011.607848
Franklin, C. L., & Raines, A. M. (2019). The overlap between OCD and PTSD: Examining self-reported symptom differentiation. Psychiatry Research, 280, 112508. doi: 10.1016/j.psychres.2019.112508
Gershuny, B. S., Baer, L., Jenike, M. A., Minichiello, W. E., & Wilhelm, S. (2002). Comorbid posttraumatic stress disorder: Impact on treatment outcome for obsessive-compulsive disorder. American Journal of Psychiatry, 159(5), 852-854. doi: 10.1176/appi.ajp.159.5.852
Gershuny, B. S., Baer, L., Parker, H., Gentes, E. L., Infield, A. L., & Jenike, M. A. (2008). Trauma and posttraumatic stress disorder in treatment-resistant obsessive-compulsive disorder. Depression and Anxiety, 25(1), 69-71. doi: 10.1002/da.20284
Gershuny, B. S., Baer, L., Radomsky, A. S., Wilson, K. A., & Jenike, M. A. (2003). Connections among symptoms of obsessive-compulsive disorder and posttraumatic stress disorder: a case series. Behaviour Research and Therapy, 41(9), 1029-1041. doi: 10.1016/S0005-7967(02)00178-X
Grabe, H. J., Ruhrmann, S., Spitzer, C., Josepeit, J., Ettelt, S., Buhtz, F., … Freyberger, H. J. (2007). Obsessive-compulsive disorder and posttraumatic stress disorder. Psychopathology, 41(2), 129-134. doi: 10.1159/000112029
Huppert, J. D., Moser, J. S., Gershuny, B. S., Riggs, D. S., Spokas, M., Filip, J., … Foa, E. B. (2005). The relationship between obsessive-compulsive and posttraumatic stress symptoms in clinical and non-clinical samples. Journal of Anxiety Disorders, 19(1), 127-136. doi: 10.1016/j.janxdis.2004.01.001
Jordan, Z., Lockwood, C., Munn, Z., & Aromataris, E. (2019). The updated Joanna Briggs Institute Model of Evidence-Based Healthcare. International Journal of Evidence-Based Healthcare, 17(1), 58-71. doi: 10.1097/XEB.0000000000000155
Kendall, P. C., Brady, E. U., & Verduin, T. L. (2001). Comorbidity in childhood anxiety disorders and treatment outcome. Journal of the American Academy of Child & Adolescent Psychiatry, 40(7), 787-794. doi: 10.1097/00004583-200107000-00013
Knowles, K. A., Sripada, R. K., Defever, M., & Rauch, S. A. M. (2019). Comorbid mood and anxiety disorders and severity of posttraumatic stress disorder symptoms in treatment-seeking veterans. Psychological Trauma: Theory, Research, Practice, and Policy, 11(4), 451-458. doi: 10.1037/tra0000383
Lafleur, D. L., Petty, C., Mancuso, E., McCarthy, K., Biederman, J., Faro, A., … Geller, D. A. (2011). Traumatic events and obsessive compulsive disorder in children and adolescents: Is there a link? Journal of Anxiety Disorders, 25(4), 513-519. doi: 10.1016/j.janxdis.2010.12.005
Langlois, F., Freeston, M. H., & Ladouceur, R. (2000). Differences and similarities between obsessive intrusive thoughts and worry in a non-clinical population: Study 1. Behaviour Research and Therapy, 38(2), 157-173. doi: 10.1016/S0005-7967(99)00027-3
McGuire, J. F., Orr, S. P., Essoe, J. K.-Y., McCracken, J. T., Storch, E. A., & Piacentini, J. (2016). Extinction learning in childhood anxiety disorders, obsessive compulsive disorder and post-traumatic stress disorder: implications for treatment. Expert Review of Neurotherapeutics, 16(10), 1155-1174. doi: 10.1080/14737175.2016.1199276
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & PRISMA Group. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Medicine, 6(7), e1000097. doi: 10.1371/journal.pmed.1000097
Morina, N., Sulaj, V., Schnyder, U., Klaghofer, R., Müller, J., Martin-Sölch, C., & Rufer, M. (2016). Obsessive-compulsive and posttraumatic stress symptoms among civilian survivors of war. BMC Psychiatry, 16(1), 115. doi: 10.1186/s12888-016-0822-9
Nacasch, N., Fostick, L., & Zohar, J. (2011). High prevalence of obsessive-compulsive disorder among posttraumatic stress disorder patients. European Neuropsychopharmacology, 21(12), 876-879. doi: 10.1016/j.euroneuro.2011.03.007
Ojserkis, R., Boisseau, C. L., Reddy, M. K., Mancebo, M. C., Eisen, J. L., & Rasmussen, S. A. (2017). The impact of lifetime PTSD on the seven-year course and clinical characteristics of OCD. Psychiatry Research, 258, 78-82. doi: 10.1016/j.psychres.2017.09.042
Pitman, R. K. (1993). Posttraumatic obsessive-compulsive disorder: A case study. Comprehensive Psychiatry, 34(2), 102-107.doi:10.1016/0010-440X(93)90054-8
Rossi, R., Niolu, C., Siracusano, A., Rossi, A., & Di Lorenzo, G. (2020). A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation. Case Reports in Psychiatry, 2020, 2616492. doi: 10.1155/2020/2616492
Sasson, Y., Dekel, S., Nacasch, N., Chopra, M., Zinger, Y., Amital, D., & Zohar, J. (2005). Posttraumatic obsessive-compulsive disorder: A case series. Psychiatry Research, 135(2), 145-152. doi: 10.1016/j.psychres.2004.05.026
Semiz, U. B., Inanc, L., & Bezgin, C. H. (2014). Are trauma and dissociation related to treatment resistance in patients with obsessive-compulsive disorder? Social Psychiatry and Psychiatric Epidemiology, 49(8), 1287-1296. doi: 10.1007/s00127-013-0787-7
Shavitt, R. G., Valério, C., Fossaluza, V., da Silva, E. M., Cordeiro, Q., Diniz, J. B., … Miguel, E. C. (2010). The impact of trauma and post-traumatic stress disorder on the treatment response of patients with obsessive-compulsive disorder. European Archives of Psychiatry and Clinical Neuroscience, 260(2), 91-99. doi: 10.1007/s00406-009-0015-3
Speckens, A. E. M., Hackmann, A., Ehlers, A., & Cuthbert, B. (2007). Imagery special issue: Intrusive images and memories of earlier adverse events in patients with obsessive compulsive disorder. Journal of Behavior Therapy and Experimental Psychiatry, 38(4), 411-422. doi: 10.1016/j.jbtep.2007.09.004
Stang, A. (2010). Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. European Journal of Epidemiology, 25(9), 603-605. doi: 10.1007/s10654-010-9491-z
Van Kirk, N., Fletcher, T. L., Wanner, J. L., Hundt, N., & Teng, E. J. (2018). Implications of comorbid OCD on PTSD treatment: A case study. Bulletin of the Menninger Clinic, 82(4), 344-359. doi: 10.1521/bumc.2018.82.4.344
